The gun may not fit your hand, but it could
There are a lot of things to think about when you are choosing a primary firearm for concealed carry purposes. Not only will you have to find the right holster configuration and see if it works for you, but you may have to think about another mode of carry if the seasons change and you have to wear a t-shirt or a winter jacket. I have carried 1911s in the past, but the more I had to wear as far as clothing, the less I liked carry them. The notion of having to disengage a manual safety after moving a vest or jacket out of the way, seemed to be too cumbersome, and after having too many problems disengaging the safety, I moved on to a different firearm.
Another thing to think about when choosing a primary CCW gun is how well your hand falls into place. If you have to constantly adjust your grip on the firearm, you may want to consider swapping out the pistol grips and try something different. Many firearms are now coming out with new generations with adjustable backstraps that will help you with fitting the gun, but to actually retain the firearm better you may want to try Hogue pistol grips or some other brand.